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Intervertebral disc lesions in diffuse idiopathic skeletal hyperostosis (DISH)
C di Girolamo1, N Pappone, C Rengo
1Rehabilitation Unit, Salvatore Maugeri Foundation I.R.C.C.S., Medical Centre of Campoli MT-Telese, BN, Italy. cardigi@tin.it
Clinical and Experimental Rheumatology
|June 16, 2001
Summary
Diffuse idiopathic skeletal hyperostosis (DISH) may predispose individuals to vertebral osteochondrosis, particularly in younger patients. This study found a higher prevalence of degenerative disc disease in DISH patients compared to controls.
Area of Science:
- Rheumatology
- Orthopedics
- Radiology
Background:
- Diffuse idiopathic skeletal hyperostosis (DISH) is a non-inflammatory condition characterized by extraskeletal ossification.
- Vertebral osteochondrosis, or degenerative disc disease, involves changes in intervertebral disc height and vertebral body morphology.
Purpose of the Study:
- To investigate the association between DISH and vertebral osteochondrosis.
- To compare the prevalence of vertebral osteochondrosis in DISH patients versus controls.
Main Methods:
- Radiographic analysis of 69 DISH patients and 68 controls.
- Diagnosis of vertebral osteochondrosis based on disc height reduction and degenerative changes.
- Age-stratified analysis using rate ratios and confidence intervals.
Main Results:
- Vertebral osteochondrosis was present in 55.1% of DISH patients and 50% of controls.
- A significantly higher prevalence of vertebral osteochondrosis was observed in younger DISH patients compared to controls (p < 0.05).
Conclusions:
- Vertebral osteochondrosis may be associated with DISH.
- DISH might play a predisposing role in the early development of vertebral osteochondrosis, potentially altering spinal biomechanics.