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Hemophagocytosis in autoimmune disease
I Sekigawa1, J Suzuki, M Nawata
1Department of Medicine, Juntendo University Izu-Nagaoka Hospital, 1129 Nagaoka, Izu-Nagaoka-cho, Tagata-gun, Shizuoka 410-2295, Japan. naga-nai@lily.onc.ne.jp
Clinical and Experimental Rheumatology
|June 16, 2001
Abstract:
Reactive hemophagocytic syndrome (HPS) is known to be associated with various autoimmune diseases, as well as infection and/or malignancy. Here we review the features of autoimmune-associated HPS and describe the possible role of autoantibodies, especially antiphospholipid antibodies (aPL), in HPS based on data obtained from our own patients.