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Comparative in vitro activity of ABT-773, a novel antibacterial ketolide
1Infectious Diseases Research, Abbott Laboratories, Abbott Park, Illinois 60064-3537, USA. angela.nilius@abbott.com
Antimicrobial Agents and Chemotherapy
|June 16, 2001
Abstract:
The in vitro activities of ABT-773, erythromycin, clarithromycin, and azithromycin were compared. ABT-773 was the most active compound against macrolide-susceptible Streptococcus pneumoniae, Streptococcus pyogenes, Staphylococcus aureus, Staphylococcus epidermidis, Listeria monocytogenes, and Enterococcus spp. and multidrug-resistant Streptococcus pneumoniae. It also had good activity against gram-negative and atypical respiratory tract pathogens and Helicobacter pylori.