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Updated: Jul 29, 2026

Biochemical Measurement of Neonatal Hypoxia
Published on: August 24, 2011
Oxygen delivery to children with hypoxaemia in small hospitals in developing countries
1Department of Paediatrics and Child Health, Addis Ababa University, Ethiopia. muhel@who.int
Insights
Nasal prongs are the safest and most effective method for oxygen delivery in developing countries. While other methods are cheaper, nasal prongs offer superior safety for treating hypoxemia in children.
Area of Science:
- Pediatric Pulmonology
- Critical Care Medicine
- Global Health
Background:
- Hypoxemia is a life-threatening condition requiring prompt oxygen therapy.
- Effective oxygen delivery is crucial, especially in resource-limited settings.
- Small hospitals in developing countries face challenges in oxygen administration.
Purpose of the Study:
- To review and evaluate oxygen delivery methods for hypoxemic patients in small hospitals in developing countries.
- To assess the safety and efficacy of various oxygen delivery modalities.
- To identify the optimal method for oxygen administration in resource-limited environments.
Main Methods:
- Systematic review of oxygen delivery methods.
- Evaluation based on cost, availability, efficiency, tolerability, humidification needs, nursing care, and safety.
- Focus on low-flow oxygen delivery systems.
Main Results:
- All low-flow methods (nasopharyngeal catheters, nasal catheters, nasal prongs) effectively oxygenate children with severe pneumonia or bronchiolitis.
- Nasal prongs are the safest option.
- Nasopharyngeal and nasal catheters are more accessible and affordable but require close supervision due to complication risks.
Conclusions:
- Nasal prongs are the preferred method for oxygen delivery in small hospitals within developing countries.
- Careful monitoring is essential when using nasopharyngeal or nasal catheters.
- Balancing cost, availability, and safety is key for effective hypoxemia management.
Abstract:
Oxygen administration is one of the most important modalities of therapy for a patient with hypoxaemia to prevent death. This review summarises the methods of oxygen delivery applicable in small hospitals in developing countries, and evaluates information about their safety and efficacy. The following criteria were considered: cost and availability, efficiency/oxygen concentration achieved, tolerability/comfort of the method, requirement of humidification, demand for nursing care, and safety of the method and complications. In summary, it is concluded that all low-flow methods, i.e., nasopharyngeal catheters, nasal catheters and prongs, are effective in the oxygenation of sick children with severe pneumonia or bronchiolitis. Nasal prongs are the safest method of oxygen delivery, but nasopharyngeal catheters and nasal catheters are more easily available and less expensive. However, if they are used, they need close supervision to avoid serious complications. Nasal prongs are the method of choice for oxygen delivery in small hospitals in developing countries.
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