Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Long axis excursion in aortic stenosis.

S Takeda1, H Rimington, N Smeeton

  • 1Department of Adult Echocardiography, Guy's and St Thomas' Hospitals NHS Trust, Lambeth Palace Road, London SE1 7EH, UK.

Heart (British Cardiac Society)
|June 19, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Diversity of electrocardiographic patterns in left main culprit acute ST-elevation myocardial infarction.

American heart journal·2025
Same author

Is a 14-day Pathway From Decision to Treat to Radiotherapy for Head and Neck Cancer Patients Feasible in the National Health Service? The Torbay Experience 5 Years On.

Clinical oncology (Royal College of Radiologists (Great Britain))·2023
Same author

Re-evaluating diagnostic thresholds for intrahepatic cholestasis of pregnancy: case-control and cohort study.

BJOG : an international journal of obstetrics and gynaecology·2021
Same author

An agenda for research and action toward diverse and just futures for life on Earth.

Conservation biology : the journal of the Society for Conservation Biology·2020
Same author

Report from the Annual Conference of the British Society of Echocardiography, October 2018, ACC Liverpool, Liverpool.

Echo research and practice·2020
Same author

Ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: a secondary analysis of the PITCHES trial.

BJOG : an international journal of obstetrics and gynaecology·2020
Same journal

Feasibility of early double sequential defibrillation in out-of-hospital cardiac arrest: the double-D randomised pilot trial.

Heart (British Cardiac Society)·2026
Same journal

Correspondence on 'When a patent foramen ovale becomes pathological' by Saji and Ohara.

Heart (British Cardiac Society)·2026
Same journal

Cost-effectiveness of N-terminal pro-B-type natriuretic peptide thresholds for echocardiography referral in primary care heart failure management.

Heart (British Cardiac Society)·2026
Same journal

Optimal timing of aspirin discontinuation after acute coronary syndrome treated with percutaneous coronary intervention: a systematic review and meta-analysis.

Heart (British Cardiac Society)·2026
Same journal

Importance of rating: the impact of establishing age and sex normative values for left ventricular strain rate.

Heart (British Cardiac Society)·2026
Same journal

Man in his 40s with palpitations.

Heart (British Cardiac Society)·2026
See all related articles

Long axis excursion is reduced in patients with aortic stenosis, even with normal systolic function. This reduced excursion is more pronounced in symptomatic severe aortic stenosis patients, potentially predicting symptom onset.

Area of Science:

  • Cardiology
  • Echocardiography
  • Cardiac Physiology

Background:

  • Aortic stenosis (AS) can impair left ventricular function.
  • Long axis excursion (LAE) is a measure of systolic function.
  • The relationship between LAE and AS severity/symptoms is not fully understood.

Purpose of the Study:

  • To assess LAE in patients with all grades of aortic stenosis and preserved transverse systolic function.
  • To compare LAE between symptomatic and asymptomatic severe aortic stenosis patients.

Main Methods:

  • Prospective comparative study involving 78 patients with AS and normal ejection fraction.
  • Echocardiographic assessment of aortic valve function and left ventricular mass.
  • M-mode measurements of LAE at the mitral annulus.

Related Experiment Videos

Main Results:

  • LAE was significantly reduced in AS patients compared to controls.
  • Reduced LAE correlated with left ventricular mass index and AS grade.
  • Symptomatic severe AS patients showed significantly lower lateral LAE and effective orifice area compared to asymptomatic patients.

Conclusions:

  • LAE is reduced in aortic stenosis, irrespective of normal fractional shortening or ejection fraction.
  • Symptomatic severe AS is associated with lower LAE than asymptomatic severe AS.
  • LAE may serve as a predictor for symptom development in aortic stenosis.