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Published on: November 23, 2013
Idiopathic polymyositis and glomerulonephritis
O F Valenzuela1, I W Reiser, J G Porush
1Division of Nephrology and Hypertension, Brookdale University Hospital and Medical Center, Brooklyn, NY, USA.
Abstract:
We report a 28-year-old male who presented with a clinical picture compatible with idiopathic polymyositis and nephrotic-range proteinuria. Muscle biopsy confirmed the diagnosis of polymyositis and a diagnostic renal biopsy demonstrated IgM mesangial glomerulonephritis. Following a short-course of prednisone, both the myositis and proteinuria resolved. Glomerulonephritis associated with idiopathic polymyositis is rare; however, since it appeared to respond to corticosteroid therapy concomitant with the improvement in the myositis, it was likely an associated immunological complication.
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