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Updated: Oct 7, 2026

Myocardial Infarction in Neonatal Mice, A Model of Cardiac Regeneration
Published on: May 24, 2016
[Efficacy of lidocaine in neonatal ischemic ventricular tachycardia]
F Benito Bartolomé1, R Funes Moñux
1Unidad de Arritmias. Laboratorio de Electrofisiología Clínica Cardíaca. Madrid. fbenito@gmx.net
Abstract:
A newborn diagnosed with D-transposition of the great arteries underwent an arterial switch operation when she was 7-days old. The coronary pattern was of type 2, with right coronary and circumflex arteries from the right sinus and anterior descending artery from the left sinus. Early post-repair electrocardiogram showed acute myocardial ischemia of the anterior septum and multiple episodes of sustained monomorphic ventricular tachycardia. Bolus and continuous infusion of intravenous lidocaine successfully terminated all episodes of ventricular tachycardia. At 6 months' follow-up the electrocardiogram was normal, without signs of myocardial ischemia or myocardial necrosis and without recurrence of ventricular tachycardia.
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