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Updated: Aug 6, 2026

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
Published on: August 11, 2008
[Epidemic outbreak of tuberculosis]
E Bernaola Iturbe1, A Barricarte Gurrea, M Urtiaga Domínguez
1Unidad de Enfermedades Infecciosas. Servicio de Pediatría. Hospital Virgen del Camino. Pamplona. bernaola@teleline.es
Rapid intervention for a tuberculosis outbreak in a nursery school was achieved through collaboration between surveillance and healthcare teams. Early detection and treatment prevented disease spread in young children.
Area of Science:
- Public Health
- Epidemiology
- Infectious Disease Control
Context:
- Tuberculosis (TB) outbreaks in childcare settings pose significant risks to vulnerable populations.
- Effective control requires swift identification and management of exposed individuals.
Purpose:
- To detail the collaborative response between epidemiological surveillance and healthcare providers during a nursery school tuberculosis outbreak.
- To highlight the effectiveness of integrated public health and clinical interventions.
Summary:
- A nursery school outbreak, initiated by an infected child minder, led to the identification of 58 exposed children and 4 other child minders.
- Tuberculin testing, radiological, and microbiological studies were performed on all exposed individuals.
- 32.8% of children were infected, with six diagnosed with active tuberculosis. Genetic analysis confirmed Mycobacterium tuberculosis transmission from the index case.
Impact:
- The study demonstrates the success of a coordinated approach in managing pediatric tuberculosis micro-outbreaks.
- Findings underscore the importance of ongoing surveillance for tuberculosis in adults working with children.
- Genetic strain analysis proved crucial for understanding transmission dynamics and guiding interventions.
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