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Pharmacogenomics: implications for laboratory medicine.

G Schmitz1, C Aslanidis, K J Lackner

  • 1Institute for Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, D-93042 Regensburg, Germany. gerd.schmitz@klinik.uni-regensburg.de

Clinica Chimica Acta; International Journal of Clinical Chemistry
|June 20, 2001
PubMed
Summary

Pharmacogenomics, the study of how genes affect drug response, is transforming drug development and personalized medicine. This growing field will significantly increase the demand for clinical laboratory diagnostic tests.

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Area of Science:

  • Clinical Laboratory Science
  • Pharmacogenomics
  • Molecular Diagnostics

Background:

  • Pharmacogenomics investigates the influence of an individual's genetic makeup on their response to drug therapy.
  • This field holds significant implications for drug development, personalized treatment strategies, and clinical in vitro diagnostics.

Purpose of the Study:

  • To review the impact of pharmacogenomics on the clinical laboratory.
  • To highlight the growing importance of pharmacogenetic testing in healthcare.

Main Methods:

  • Literature review focusing on the intersection of pharmacogenomics and clinical laboratory practices.
  • Analysis of trends in molecular biology testing and diagnostic test demand.

Main Results:

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  • Pharmacogenomics is poised to significantly influence drug development and treatment paradigms.
  • There is a projected increase in demand for rapid and reliable pharmacogenetic diagnostic tests.

Conclusions:

  • Clinical laboratories will play a crucial role in the implementation of pharmacogenomic advancements.
  • Pharmacogenetic tests are expected to constitute a substantial portion of future molecular biology testing.