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Peripheral nonulcerative keratitis as a presenting sign of microscopic polyangiitis
J K Darlington1, M J Mannis, W A Segal
1Department of Ophthalmology, University of California, Davis, California, USA.
Cornea
|June 20, 2001
Abstract
Purpose:
To report a 16-year-old woman who had peripheral keratitis as a presenting sign of microscopic polyangiitis (MPA), which rapidly progressed to acute renal failure.
Method:
Case report.
Results:
The patient's vasculitis was diagnosed by renal biopsy, which was evaluated with histologic, immunofluorescence, and electron microscopy. The diagnosis was confirmed by laboratory study, which showed a positive antimyeloperoxidase antibody.
Conclusion:
MPA may rarely present with ocular findings and should be considered in the differential diagnosis when a patient has peripheral keratitis.