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Updated: Mar 31, 2026

Motility of Single Molecules and Clusters of Bi-Directional Kinesin-5 Cin8 Purified from S. cerevisiae Cells
Published on: February 2, 2022
Walking on two heads: the many talents of kinesin
1Adolf-Butenandt-Institut, Zellbiologie, University of Munich, Schillerstrasse 42, 80336 Munich, Germany. guenther.woehlke@lrz.uni-muenchen.de
Abstract:
The gallop of a race horse and the minute excursions of a cellular vesicle have one thing in common: they are based on the directional movement of proteins termed molecular motors -- many trillions in the case of the horse, just a few in the case of the cell vesicle. These tiny machines take nanometre steps on a millisecond timescale to drive all biological movements. Over the past 15 years new biochemical and biophysical approaches have allowed us to take a giant step forward in understanding the molecular basis of motor mechanics.
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