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Updated: Oct 7, 2026

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)
Published on: August 4, 2018
[Basic principles of physics in optical imaging of the human eye]
1Ustav lékarské biofyziky, Univerzita Karlova v Praze, Lékarská fakulta v Hradci Králové.
Abstract:
Creation of a real picture of the observed object on the retina by optical system of the eye is the primary physical condition of the visual perception. Absorption of the light energy initiates the sequence of further physicochemical, biochemical and psychophysiological events partially taking place already in the retina but mostly in the higher cerebral and spinal centres. So the visual perception and its final evaluation is the result of a complicated complex of processes where the optical imaging itself plays the role of the starting factor. In the publication particularly the physical substance of the optical imaging on refraction surfaces between media with different refraction index has been accentuated. The laws of reflection and refraction and their origin are derived in the terms of the physical (Maxwell equations) and geometrical (Fermat principle, principle of the mutual independence of light beams) optics. In the adequate extent the development and structure of the eye and the whole visual complex, the bases of the quantification of the visual perception and contemporary opinions on mechanisms of the colour vision (trichromatic theory) have been described. The publication is completed by a mathematical appendix explaining some relations usually absent in the biomedical literature.
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