Related Experiment Video
Updated: Jan 19, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
Published on: November 9, 2016
Binding of the products of prothrombin activation to human platelets
Abstract:
Binding of prothrombin and activation intermediates 1 and 2 to human platelets was tested with 125-I-labeled protein preparations. None of these precursors of thrombin bound to platelets under conditions in which high affinity binding of thrombin was observed,nor did they cause platelet aggregation or serotonin release. The molecular conformation required for binding to platelets as well as for induction of platelet aggregation and release is present, therefore, only after the final step in prothrombin activation.
Related Concept Videos
Heart Failure V: Medical Management
Myocarditis III: Medical Management
Endocarditis III: Medical Management
06:59A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
Inhaled Medications
Preparing and Administering Inhaled Medications
Inhaled medications are prescribed for conditions affecting the bronchi, which branch off of the trachea, and bronchioles, which are progressively smaller conducting airways spread throughout the lung tissue. These conditions can be classified as acute (i.e., temporary, with quick onset) or chronic (i.e., persistent and/or recurrent symptoms lasting months to years). Common acute conditions...