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Published on: May 30, 2019
Clinical presentation of childhood malaria in Savannakhet province, Lao PDR
O Anothay1, T Pongvongsa, N Maharat
1Savannakhet Provincial Hospital, Lao PDR.
Insights
Delayed treatment for childhood malaria in Laos is linked to altered consciousness levels. Early intervention is crucial for better outcomes in pediatric malaria cases.
Area of Science:
- Tropical Medicine
- Pediatrics
- Infectious Diseases
Background:
- Childhood malaria remains a significant health concern in endemic regions.
- Understanding the clinical presentation is vital for timely diagnosis and management.
- Savannakhet Province, Lao People's Democratic Republic, faces a considerable burden of pediatric malaria.
Purpose of the Study:
- To describe the clinical features of malaria in children aged 1-14 years.
- To investigate the association between malaria severity and treatment initiation or delay.
- To identify clinical indicators of severe malaria in a pediatric population.
Main Methods:
- A descriptive study involving 92 children (1-14 years) with confirmed malaria.
- Data collection on clinical signs, symptoms, and treatment history.
- Statistical analysis to determine associations between clinical parameters and disease duration.
Main Results:
- Over half of the children (60.9%) experienced illness for less than 3 days before hospitalization.
- Significant associations were found between consciousness levels and illness duration (>3 days associated with altered consciousness).
- Common symptoms included vomiting (51.1%), hepatomegaly (19.6%), and splenomegaly (20.7%).
Conclusions:
- Delayed treatment in childhood malaria is associated with neurological complications, specifically altered consciousness.
- Clinical presentation varies, with vomiting and organomegaly being frequent.
- Early diagnosis and prompt treatment are critical for improving outcomes in pediatric malaria patients.
Abstract:
A descriptive study on the clinical presentation of childhood malaria was conducted in Savannakhet Province, Lao People's Democratic Republic. It is aimed to describe the clinical features and to determine the association between the severity of malaria and the initiation or delay of treatment. A total number of 92 children 1-14 years of age with confirmed malaria diseases were enrolled in this study. Fifty-six cases (60.9%) had illness for less than 3 days before hospitalized and 36 cases (39.1%) for more than 3 days. Twenty-nine cases (31.5%) had self antimalarial medication before admission (9 cases of chloroquine, 16 cases of quinine and 4 cases of artesunate). Ten cases (10.9%) had abnormal consciousness of which 7 cases (7.6%) had confusion but responded to verbal command and 3 cases (3.3%) were in coma not respond to painful stimuli but had reflex. Two cases 2.2%) had convsulsions, 11 cases (12.0%) had dehydration, 47 cases (51.1%) had vomiting, 18 cases (19.6%) had hepatomegaly and 19 cases (20.7%) had splenomegaly. There was a statistically significant association between consciousness levels and the duration of illness before admission < or = 3 days and > 3 days (p = 0.01) while there is no significant difference between parasitemia density and the duration of illness before admission (p > 0.05).
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