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Hypercholesterolemia in the Elderly: Evaluation and Treatment.

Peter F. Stein1

  • 1Section of Endocrinology and Nutrition, Department of Medicine, Medical College of Georgia, Augusta, GA.

The American Journal of Geriatric Cardiology
|May 1, 1997
PubMed
Summary

High cholesterol (hypercholesterolemia) is a risk factor for heart disease. This review examines its role in older adults and the benefits versus risks of cholesterol-lowering therapy in this population.

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Area of Science:

  • Cardiology
  • Geriatrics
  • Vascular Medicine

Background:

  • Hypercholesterolemia is a known risk factor for atherosclerotic vascular disease.
  • Cholesterol treatment reduces coronary events in patients with and without prior coronary disease.

Purpose of the Study:

  • To discuss hypercholesterolemia's role in coronary artery disease pathogenesis in the elderly.
  • To review the benefits and risks of cholesterol-lowering therapy in older adults.

Main Methods:

  • Literature review of studies on hypercholesterolemia and cardiovascular disease in the elderly.
  • Analysis of the established benefits and risks of lipid-lowering treatments in geriatric populations.

Main Results:

  • The association between hypercholesterolemia and cardiovascular risk is less defined in the elderly.

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  • The benefits of treating elevated cholesterol in older adults are less established compared to younger populations.
  • Conclusions:

    • Further research is needed to clarify the specific benefits and risks of hypercholesterolemia treatment in the elderly.
    • Individualized treatment strategies may be necessary for managing cholesterol in older adults.