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Treatment of Hypertension in the Institutionalized Elderly
1Hebrew Hospital Home, Bronx, NY, and the Department of Geriatrics and Adult Development, Mount Sinai School of Medicine, New York, NY.
Insights
Antihypertensive therapy for elderly individuals aims to lower blood pressure below 140/90 mm Hg. Initial drug choices include diuretics or beta-blockers, with subsequent treatments tailored to individual medical conditions.
Area of Science:
- Geriatric Medicine
- Cardiology
- Pharmacology
Background:
- Hypertension management in elderly institutionalized persons requires specific therapeutic goals.
- Target blood pressure for elderly individuals is generally less than 140/90 mm Hg.
- Specific targets exist for diastolic hypertension (80-85 mm Hg) and in cases with comorbidities.
Purpose of the Study:
- To outline the goals and strategies for antihypertensive therapy in elderly institutionalized patients.
- To guide the selection of initial and subsequent antihypertensive medications.
- To emphasize the importance of considering associated medical conditions in treatment decisions.
Main Methods:
- The abstract outlines treatment guidelines based on blood pressure levels and patient conditions.
- It suggests initial drug choices (diuretics, beta-blockers) supported by clinical trial evidence.
- It details a stepwise approach for adding second and third-line antihypertensive agents.
Main Results:
- Elderly individuals with stage 2 or 3 hypertension, stage 1 with target organ damage, cardiovascular disease, or diabetes require immediate drug therapy alongside lifestyle changes.
- Diuretics or beta-blockers are recommended as initial antihypertensive drugs for elderly patients without other medical conditions.
- Treatment involves adding drugs from different classes if initial therapy is insufficient, with diuretics often used as a second-line option.
Conclusions:
- Antihypertensive drug selection in the elderly should be individualized based on comorbidities.
- A stepwise approach involving up to three drug classes may be necessary to achieve blood pressure goals.
- Identifying and treating secondary hypertension is crucial.
Abstract:
The goal of antihypertensive therapy in elderly institutionalized persons is to reduce the blood pressure to less than 140/90 mm Hg if possible. Elderly persons with diastolic hypertension should have their diastolic blood pressure lowered to 80-85 mm Hg. Elderly persons with stage 2 or 3 hypertension, stage 1 hypertension and target organ damage, evidence of clinical cardiovascular disease, or diabetes mellitus should be treated with antihypertensive drug therapy immediately in addition to lifestyle modification. The initial antihypertensive drug in elderly persons without associated medical conditions should be a diuretic or à -blocker because these drugs have been shown to decrease cardiovascular morbidity and mortality in controlled clinical trials. The initial antihypertensive drug in elderly persons should depend on the associated medical condition. If a second antihypertensive drug is indicated, a drug from another class should be administered. If a diuretic is not the initial drug, it is usually indicated as the second drug. If the antihypertensive response is inadequate after reaching the full dose of two classes of drugs, a third drug from another class should be added. Causes of secondary hypertension should be identified and treated. (c)2000 by CVRR, Inc.
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