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Updated: Jul 31, 2026

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure
Published on: August 25, 2017
[Prognostication of obstructive syndrome in patients with chronic bronchitis considering hereditary factors]
Aim:
To propose method of accurate prediction of chronic obstructive pulmonary disease (COPD) at early stages of development.
Material And Methods:
92 males with COPD and 55 males with chronic non-obstructive bronchitis aged 38 to 72 years were examined according to a technique which identifies hereditary predisposition to multifactor diseases and using an algorithm based on multivariate analysis.
Results:
An original mathematical model is proposed which can quantitatively examine and range by influence the role of environmental and hereditary factors in development of COPD.
Conclusion:
Detection of hereditary predisposition to COPD may be one of the objective criteria to recommend giving up smoking and for occupational orientation.
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