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Influenza Virus Propagation in Embryonated Chicken Eggs
Published on: March 19, 2015
Adenovirus pathogenicity in immature ostriches
J El-Attrache1, P Villegas, B O'Connor
1Department of Avian Medicine, College of Veterinary Medicine, University of Georgia, Athens 30602-4875, USA.
Avian Diseases
|June 22, 2001
Summary
Two avian adenoviruses were isolated from young ostriches with fading chick syndrome. However, pathogenicity trials revealed these viruses were not infectious in ostrich chicks.
Area of Science:
- Veterinary Virology
- Avian Pathology
- Ostrich Medicine
Background:
- Fading chick syndrome (FCS) is a significant concern in young ostriches.
- Group I avian adenoviruses are suspected causative agents of FCS in ostriches under 8 weeks of age.
Purpose of the Study:
- To isolate and identify avian adenoviruses associated with FCS in ostriches.
- To determine the pathogenicity of these isolated viruses in immature ostriches.
Main Methods:
- Isolation of viruses in primary chicken embryo liver cells.
- Identification using virus neutralization assays.
- Pathogenicity assessment through experimental inoculation of ostrich chicks.
Main Results:
- Two group I avian adenovirus isolates were successfully obtained from affected ostrich chicks.
- Virus neutralization confirmed the identity of the isolates.
- Pathogenicity trials demonstrated that these isolates were noninfectious in immature ostriches.
Conclusions:
- The isolated group I avian adenoviruses, while associated with cases of FCS, do not appear to be directly infectious or pathogenic in young ostriches.
- Further research is needed to elucidate the etiology of fading chick syndrome in ostriches.
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