Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Salmonella pathogenicity islands encoding type III secretion systems.

I Hansen-Wester1, M Hensel

  • 1Lehrstuhl für Bakteriologie, Max von Pettenkofer-Institut, LMU München, Germany.

Microbes and Infection
|June 22, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Retrospective Analysis of Aetiological Agents Associated with Pulmonary Mycosis Secondary to Enteric Salmonellosis in Six Horses by Panfungal Polymerase Chain Reaction.

Journal of comparative pathology·2020
Same author

Phylogenetic analysis of Histoplasma capsulatum var duboisii in baboons from archived formalin-fixed, paraffin embedded tissues.

Medical mycology·2018
Same author

Digital palpation of the pilot balloon vs. continuous manometry for controlling the intracuff pressure in laryngeal mask airways.

Anaesthesia·2016
Same author

[Continuous cuff pressure measurement during laryngeal mask anesthesia : An obligatory measure to avoid postoperative complications].

Der Anaesthesist·2016
Same author

Overinflation of the cuff and pressure on the neck reduce the preventive effect of supraglottic airways on pulmonary aspiration: an experimental study in human cadavers.

British journal of anaesthesia·2016
Same author

Hodgkin lymphoma is as common as non-Hodgkin lymphoma in HIV-positive patients with sustained viral suppression and limited immune deficiency: a prospective cohort study.

HIV medicine·2014
Same journal

The extent of monocytic myeloid suppressor cells induction determines the host immune response during Mycobacterium avium infection.

Microbes and infection·2025
Same journal

Culture-attenuated pathogenic Leptospira lose the ability to survive complement lytic activity due to decreased C4BP uptake.

Microbes and infection·2025
Same journal

Exploring the link between genetically predicted plasma cathepsins and COVID-19: A mendelian randomization study of susceptibility and severity.

Microbes and infection·2025
Same journal

Laboratory parameters and serum tube agglutination test as markers for brucellosis treatment response.

Microbes and infection·2025
Same journal

Corrigendum to "Lactococcus lactis and Bifidobacterium longum attenuate Clostridioides difficile- or Clostridium symbiosum-induced colitis and depression/anxiety-like behavior in male mice" [Microb Infect 27(7) (2025) 105560].

Microbes and infection·2025
Same journal

Disrupted Microbiome-Metabolome networks underlie gut barrier and immune imbalance in severe fever with thrombocytopenia syndrome.

Microbes and infection·2025
See all related articles

Salmonella enterica pathogenicity islands (SPIs) SPI1 and SPI2 are crucial for bacterial virulence. This review compares their genetic organization, evolution, regulation, and functions in Salmonella infection.

Area of Science:

  • Microbiology
  • Molecular Biology
  • Genetics

Background:

  • Salmonella enterica is a significant human pathogen.
  • Pathogenicity islands (SPIs) are key virulence determinants in Salmonella.
  • Two major SPIs, SPI1 and SPI2, encode type III secretion systems (T3SS).

Purpose of the Study:

  • To review and compare Salmonella pathogenicity islands (SPIs) SPI1 and SPI2.
  • To elucidate the genetic organization, evolution, regulation, and functions of SPI1 and SPI2.
  • To provide a comprehensive understanding of these virulence factors in Salmonella pathogenesis.

Main Methods:

  • Literature review and synthesis of existing research.
  • Comparative analysis of genetic data for SPI1 and SPI2.
  • Functional analysis of T3SS encoded by SPI1 and SPI2.

Related Experiment Videos

Main Results:

  • SPI1 is essential for Salmonella invasion of host cells.
  • SPI2 is critical for systemic infection and intracellular bacterial survival.
  • Both SPIs exhibit distinct yet complementary roles in Salmonella pathogenesis.

Conclusions:

  • SPI1 and SPI2 are distinct but cooperative virulence systems in Salmonella.
  • Understanding these SPIs is vital for developing effective anti-Salmonella strategies.
  • Further research into SPI regulation and function can reveal novel therapeutic targets.