The Yersinia high-pathogenicity island: an iron-uptake island
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Updated: Oct 6, 2026

Quantifying Yersinia pseudotuberculosis Type III Secretion System Activity Following Iron Starvation and Anaerobic Growth
Published on: May 31, 2024
1Laboratoire des Yersinia, Unité des bactériologie moléculaire et médicale, Institut Pasteur, 28, rue du Dr. Roux, 75724 cedex 15, Paris, France. carniel2@pasteur.fr
Abstract:
Highly pathogenic Yersinia carry a pathogenicity island termed high-pathogenicity island (HPI). The Yersinia HPI comprises genes involved in the synthesis of the siderophore yersiniabactin and can thus be regarded as an iron-uptake island. A unique characteristic of the HPI is its wide distribution among different enterobacteria such as Escherichia coli, Klebsiella, Citrobacter and Salmonella. Other types of iron-uptake systems are also carried by different pathogenicity islands in enterobacteria.
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