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Pathogenicity and resistance islands of staphylococci
R P Novick1, P Schlievert, A Ruzin
1Molecular Pathogenesis Program, Skirball Institute of Biomolecular Medicine, New York University Medical Center, New York, NY 10016, USA. novick@saturn.med.nyu.edu
Microbes and Infection
|June 22, 2001
Abstract:
Variable genetic elements including plasmids, transposons and prophages are involved in pathogenesis and antibiotic resistance, and are an important component of the staphylococcal genome. This review covers a set of newly described variable chromosomal elements, pathogenicity and resistance islands, carrying superantigen and resistance genes, especially toxic shock and methicillin resistance, respectively.