Regulation of coremium morphogenesis in Penicillium claviforme

Coremia of Penicillium claviforme develop in three stages; primordium formation, elongation, and sporulation. Primordium formation was induced by external nutrients, while starvation initiated the differentiation of primordia into coremia with sporeheads. There is strong evidence that external nutrients are not taken up during this differentiation. Continued sporulation by mature coremia again required an external nutrient supply.