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Updated: Aug 16, 2026

Development of a Hepatitis B Virus Reporter System to Monitor the Early Stages of the Replication Cycle
Published on: February 1, 2017
Improving hepatitis B immunization among high-risk adolescents: a low-cost intervention on the Mexico-United States
K M O'Rourke1, T E Redlinger, A M Steege
1Department of Biometry and Epidemiology, 135 Rutledge Ave, Suite 1134, Charleston, South Carolina 29425, USA. orourkek@musc.edu
Objective:
To analyze factors associated with hepatitis B immunization adherence among adolescents attending a sexually transmitted disease (STD) clinic in El Paso, a city in Texas that is on the border between Mexico and the United States of America.
Methods:
In this cohort study with 248 adolescents we obtained data on demographics and health beliefs through personal interviews and medical record abstraction. We monitored each of the individuals for 8 months to determine whether the adolescents received a first, second, and third dose of the hepatitis B vaccine.
Results:
Overall, 32% of the adolescents received the first immunization, 9% the second, and 2% the third. The strongest predictor of receiving either one or two doses was providing the vaccine at the STD clinic as opposed to referring adolescents to a separate vaccination clinic (relative risk (RR) for receiving the first immunization = 7.3; RR for receiving the second immunization = 3.8). Several health beliefs were also associated with receiving vaccinations.
Conclusions:
The results of our study indicate that hepatitis B vaccination programs can be improved through such steps as providing vaccinations at a convenient site, educating adolescents about hepatitis B risk factors, and emphasizing the difficulty of treating hepatitis B infection.
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