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Experience with juvenile polyps in North American children: the need for pancolonoscopy
S K Gupta1, J F Fitzgerald, J M Croffie
1Division of Pediatric Gastroenterology, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis 46202-5225, USA.
Insights
Pancolonoscopy (PC) is recommended for children with juvenile polyps (JP). Many JPs are found in the upper colon, and PC reduces the need for repeat procedures and potential risks.
Area of Science:
- Pediatric Gastroenterology
- Colorectal Surgery
- Pediatric Endoscopy
Background:
- Juvenile polyps (JP) are common in children, often presenting with painless rectal bleeding.
- The extent of colonoscopy required for diagnosis and management of JP is debated.
Purpose of the Study:
- To evaluate the necessity of pancolonoscopy (PC) for all children diagnosed with juvenile polyps.
- To determine the prevalence and location of juvenile polyps in a North American pediatric cohort.
Main Methods:
- Retrospective chart review of 184 pediatric patients with 331 juvenile polyps over a 9-year period.
- Analysis of polyp location based on endoscopic findings during 195 procedures, including pancolonoscopies (PC).
Main Results:
- Painless rectal bleeding was the most frequent symptom.
- Pancolonoscopy revealed proximal polyps in 37% of cases, with 12% having only proximal polyps.
- Five patients required re-endoscopy due to persistent symptoms from missed proximal polyps.
Conclusions:
- Pancolonoscopy should be the initial procedure for suspected juvenile polyps in children.
- PC identifies proximal polyps, prevents repeat procedures, and mitigates risks associated with missed lesions.
- While most JPs are left-sided, proximal detection is significant, warranting a complete examination.
Abstract:
We report a recent experience with juvenile polyps (JP) in a large cohort of North American children to determine if a pancolonoscopy (PC) is needed in all children with suspected polyps. We reviewed hospital charts of all patients with JP seen over a 9-yr period (January, 1990-October, 1998). A total of 331 JP were encountered during 195 procedures in 184 patients (64% males, 88% white, mean age 5.93 yr [range 0.42-15.5 yr], median age 4.84 yr). Painless rectal bleeding was the commonest symptom. PC was performed in 42% (82/195) of procedures, and 177 JP were encountered: 54% (97/177) were in the rectosigmoid colon, 14% (24/177) were in the descending colon, and 32% (56/177) were proximal to the splenic flexure (i.e., proximal polyps). Overall, proximal polyps were seen in 37% (31/82) of PC. Only proximal polyps were noted in 12% (10/82) of PC. Five patients were re-endoscoped after an initial limited examination because of continuing symptoms from proximal polyps. All but one of the polyps had typical features of a JP on histological examination. Though most JP are located in the left colon, a PC should be the initial procedure because: 1) 37% of PC revealed proximal polyps, 2) 32% of polyps were located proximal to splenic flexure, 3) persistence of symptoms from missed proximal polyp(s) necessitates a repeat study with attendant risks, and 4) there is a possibility of malignant transformation in an unidentified JP.
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