Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Epileptic seizures and sleep-wake rhythm.

H Horita1

  • 1Department of Paediatrics, Social Insurance Kamata General Hospital, Tokyo, Japan. hos.tak2@f5.dion.ne.jp

Psychiatry and Clinical Neurosciences
|June 26, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Extremely small-diameter, high-density, radio frequency, plasma sources and central gas feeding for next-generation electrodeless plasma thrusters.

The Review of scientific instruments·2020
Same author

Autophagy regulates selective HMGB1 release in tumor cells that are destined to die.

Cell death and differentiation·2008
Same author

Acute-myeloid-leukemia-targeted toxins kill tumor cells by cell-type-specific mechanisms and synergize with TRAIL to allow manipulation of the extent and mechanism of tumor cell death.

Leukemia·2007
Same author

Coaxial-slot antenna for interstitial microwave thermal therapy and its application to clinical trial.

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference·2007
Same author

The correlation between penile tumescence measured by the erectometer and penile rigidity by the RigiScan.

International journal of urology : official journal of the Japanese Urological Association·2002
Same author

Extraperitoneal bladder rupture secondary to rectal impalement.

International journal of urology : official journal of the Japanese Urological Association·2002
Same journal

Response to commentary "Hypnotic-associated falls across the diurnal cycle: Pharmacokinetic signal or delirium rhythm?"

Psychiatry and clinical neurosciences·2026
Same journal

Editorial: Hyperbaric oxygen therapy in psychiatry.

Psychiatry and clinical neurosciences·2026
Same journal

Reevaluation of Lateral Ventricular Enlargement in Psychiatry.

Psychiatry and clinical neurosciences·2026
Same journal

Characterizing social motivation deficits in treatment-resistant schizophrenia: Evidence from social incentive performance.

Psychiatry and clinical neurosciences·2026
Same journal

Response to [Time zero alignment in target trial emulation of VMAT2 inhibitors versus anticholinergics for tardive dyskinesia].

Psychiatry and clinical neurosciences·2026
Same journal

Association between initial 30-day cumulative clozapine dose and risk of agranulocytosis: A nationwide register-based cohort study.

Psychiatry and clinical neurosciences·2026
See all related articles

This study analyzed seizure patterns in 25 children with epilepsy, finding that clinical seizures and subclinical discharges vary significantly between waking and sleeping states, impacting different epilepsy syndromes.

Area of Science:

  • Pediatric Neurology
  • Epileptology
  • Sleep Medicine

Background:

  • Epilepsy in children presents diverse clinical manifestations.
  • Seizure occurrence and characteristics can be influenced by the sleep-wake cycle.
  • Understanding these patterns is crucial for accurate diagnosis and management.

Purpose of the Study:

  • To investigate the relationship between seizure occurrence (clinical and subclinical) and the sleep-wake cycle in children with various epilepsy syndromes.
  • To differentiate seizure patterns across different pediatric epilepsy types.

Main Methods:

  • Retrospective analysis of 25 pediatric epilepsy cases.
  • Classification of epilepsy syndromes including West syndrome, Lennox-Gastaut syndrome, childhood absence epilepsy (CAE), and localization-related epilepsies.

Related Experiment Videos

  • Correlation of clinical seizure occurrence and subclinical ictal discharges with waking and sleeping states (REM and non-REM sleep).

    • Main Results:

    • Clinical seizures occurred during waking states in 14 children, during sleep in 5, and diffusely in 6.
    • Subclinical ictal discharges were observed during REM sleep in West syndrome, and during both REM and non-REM sleep in CAE and epilepsy with myoclonic absences (EMA).
    • Lennox-Gastaut syndrome and localization-related epilepsies exhibited seizure patterns across both waking and sleeping states.

    Conclusions:

    • Seizure occurrence and electrographic patterns in pediatric epilepsy are significantly associated with the sleep-wake cycle.
    • Specific epilepsy syndromes demonstrate distinct patterns of clinical and subclinical seizure activity during different sleep stages.
    • These findings underscore the importance of considering the sleep-wake cycle in the comprehensive evaluation of childhood epilepsy.