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[Risk factors involved in symmetrical distal diabetic neuropathy]
N Gómez-Viera1, A Soto-Lavastida, H Roselló-Silva
1Servicio de Neurología; Hospital Clínico Quirúrgico Hermanos Ameijeiras, La Habana, 10300, Cuba. vdc@hha.sld.cu
Revista De Neurologia
|June 26, 2001
Summary
Diabetic neuropathy affects 30% of diabetes patients. Key risk factors include smoking, high cholesterol, poor diabetes control, and longer diabetes duration.
Area of Science:
- Neurology
- Endocrinology
- Public Health
Background:
- Diabetic neuropathy is a prevalent complication of diabetes mellitus, significantly impacting patient quality of life.
- The specific risk factors contributing to diabetic neuropathy remain incompletely understood.
Purpose of the Study:
- To ascertain the incidence of symmetrical distal diabetic neuropathy.
- To identify associated risk factors for its development in the studied population.
Main Methods:
- A cross-sectional study involving 200 patients with type 1 or type 2 diabetes mellitus.
- Clinical neurological examinations and neurophysiological tests were performed for diagnosis.
- Statistical analysis, including chi-squared tests and relative risk estimation, was used to compare patients with and without neuropathy.
Main Results:
- The frequency of symmetrical distal diabetic neuropathy was found to be 30.0%.
- Significant risk factors identified were smoking (RR=2.59), elevated serum cholesterol (RR=4.12), poor glycemic control (RR=4.13), and longer diabetes duration (RR=2.01).
- Associated disorders, such as arterial hypertension (RR=1.90), also increased risk.
Conclusions:
- Symmetrical distal diabetic neuropathy is a common complication in diabetes mellitus.
- Several modifiable and non-modifiable risk factors are significantly associated with its occurrence.