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Updated: Oct 5, 2026

Establishment of Orthotopic Patient-derived Xenograft Models for Brain Tumors using a Stereotaxic Device
Published on: May 2, 2025
[Complications of stereotaxic surgery for cerebral tumors. Minimal access neurosurgery]
A Padrón-Sánchez1, G López-Flores, I García-Maeso
1Clínica de Neurocirugía, Centro Internacional de Restauración Neurológica (CIREN), La Habana, 11300, Cuba. padron@neuro.sld.cu
Introduction:
Complications of neurosurgery include the clinical, neurological and neurosurgical aspects. Their prevention and correction depend on satisfactory preoperative assessment and close postoperative follow-up. Although minimum access neurosurgery reduces some problems, the complexity and depth of many cerebral lesions cause problems. Therefore it is important to adhere to the above principles to obtain good results.
Objectives:
To determine the clinical complications, their early detection and course to be followed when they occur.
Patients And Methods:
We studied 29 patients with intracranial tumors operated on using stereotaxic surgery during a period of two years. They were evaluated before and after surgery and the complications recorded.
Results:
We discuss the most significant clinical aspects of peri-operative management. The main complications found were lower respiratory tract infection and hyperglycemia.
Conclusions:
These results show the need for suitable management, even in minimum access surgery, in patients with cerebral tumors operated on using stereotaxis and underline the most significant complications.