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Related Experiment Videos

[Infantile bilateral striate necrosis].

P Garcés1, A R Reyes, R Reig

  • 1Cuidados Intensivos Pediátricos.Medicina Intensiva; Hospital General Universitario de Alicante, Alicante, 03010, España. nurico@jazzfree.com

Revista De Neurologia
|June 26, 2001
PubMed
Summary

Necrosis of the basal ganglia (NBG) is rare in children and can follow infections. This case shows NBG lesions resolving, suggesting a post-infectious cause with good prognosis.

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Area of Science:

  • Pediatric Neurology
  • Neuroimaging
  • Infectious Diseases

Background:

  • Necrosis of the basal ganglia (NBG) is an uncommon pediatric condition.
  • NBG is associated with various conditions including metabolic disorders, infections, and hypoxic-ischemic encephalopathies.
  • Common clinical features include altered consciousness, movement disorders, spasticity, and seizures.

Observation:

  • A case of an eight-year-old girl with acute neurological dysfunction post-gastroenteritis.
  • Initial CT scans suggested an intracranial tumor; MR imaging revealed bilateral basal ganglia hypodensities.
  • Follow-up MR imaging showed near-complete resolution of these lesions within three months.

Findings:

  • The observed resolution of basal ganglia lesions supports a diagnosis of post-infectious NBG.

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  • Magnetic resonance (MR) imaging is highly specific for diagnosing basal ganglia involvement.
  • While the clinical course varies, a history of infection may indicate a better prognosis.

    • Implications:

    • Advanced imaging techniques like CT and MR facilitate the diagnosis of selective basal ganglia involvement.
    • Prompt diagnosis and management, potentially including corticosteroids, can lead to good recovery without sequelae.
    • Further research into effective treatments for NBG is warranted, despite some therapies showing limited efficacy.