Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Juvenile myoclonic epilepsy].

J Salas-Puig1, S Calleja, L Jiménez

  • 1Servicio de Neurología; Hospital General de Asturias, Oviedo, España. jsalasp@meditex.es

Revista De Neurologia
|June 26, 2001
PubMed
Summary

Juvenile myoclonic epilepsy (JME) has a rich history. Valproic acid remains the primary treatment, with other options available, but relapses are common if treatment stops.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Treatment outcomes in sinonasal aspergillosis in dogs in the United Kingdom: 436 cases (2011-2021).

The Journal of small animal practice·2025
Same author

Diagnostic findings in sinonasal aspergillosis in dogs in the United Kingdom: 475 cases (2011-2021).

The Journal of small animal practice·2024
Same author

Management of cerebral venous thrombosis in Spain: MOTIVATE descriptive study.

Neurologia·2023
Same author

Attempts to use breeding approaches in Aedes aegypti to create lines with distinct and stable relative Wolbachia densities.

Heredity·2022
Same author

Overnight switch from levetiracetam to brivaracetam. Safety and tolerability.

Epilepsy & behavior reports·2021
Same author

Management of cerebral venous thrombosis in Spain: MOTIVATE descriptive study.

Neurologia·2021

Area of Science:

  • Neurology
  • Epileptology

Context:

  • Review of the historical progression of Juvenile Myoclonic Epilepsy (JME) since its initial descriptions.
  • Highlighting key contributions from Herpin, Janz, Christian, and Delgado-Escueta in defining JME.
  • Acknowledging the genetic basis discovered for JME in certain patient cohorts.

Purpose:

  • To provide a comprehensive overview of Juvenile Myoclonic Epilepsy (JME).
  • To discuss the diagnostic considerations and differential diagnoses for JME.
  • To review current and alternative treatment strategies for JME.

Summary:

  • JME exhibits striking homogeneity in clinical and neurophysiological characteristics globally.
  • Diagnosis is straightforward when the syndrome is recognized; however, differential diagnosis is crucial for some patients.
  • Valproic acid is the first-line treatment; alternatives include primadone, lamotrigine, and topiramate.

Impact:

  • Facilitates easier diagnosis of JME by raising awareness of its characteristics.
  • Informs clinical practice regarding optimal pharmacotherapy for JME.
  • Emphasizes the importance of sustained treatment adherence to prevent relapse in JME patients.

Related Experiment Videos