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Updated: Aug 18, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
[Small cell lung cancer revealed by extramembranous glomerulonephritis]
M Grivaux1, D Renault, J C Gallois
1Service de Pneumologie, Centre Hospitalier de Meaux, 6-8 rue St Fiacre, BP 218, 77104 Meaux. pneumomeaux@csi.com ou m-grivaux@ch-meaux.fr
Abstract:
We describe a case of small-cell lung cancer limited to the thorax but with malignant pleural effusion in a 47-year-old man that was revealed by a nephrotic syndrome due to membranous glomerulonephritis (MGN). Chemotherapy led to a partial tumor response with total resolution of the nephrotic syndrome. Tumor relapse did not provoke proteinuria. Primary lung cancer is the cause of about 3% of all cases of MGN and 40% of tumor-related MGN. There are 49 cases of tumor-related MGN in the literature, including 9 cases of small-cell lung cancer.
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