Related Experiment Video
Updated: Aug 15, 2026

A Murine Model of Irreversible and Reversible Unilateral Ureteric Obstruction
Published on: December 20, 2014
Abstract:
An explanation was sought as to why the ureter becomes tortuous with increased intraluminal pressure. Changes in ureteral diameter and length, secondary to increased intraluminal pressure, were measured in different pathologic conditions and these changes were compared to similar ones in a non-biologic material (latex rubber tubing). It was demonstrated that these changes were anisotropic and remarkably similar under quite different pathologic conditions. Ureteral tortusity occurring secondary to increased intraluminal pressure may be related to anisotropic expansion of a tube with both ends in a fixed position.
Related Concept Videos
Urine: Physical and Chemical Properties
The concentration of these solutes varies, with urea being the most abundant nitrogenous waste product. Other solutes include sodium, chloride, potassium, phosphate,...
Ureters
Urinary Bladder
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
Urethra
The anatomy of the urethra differs between males and females. In females, the urethra is short, measuring about 3–4 cm in length, and opens anterior to the vaginal opening. In males, the urethra is longer and passes through the penis, serving dual purposes: expelling urine and ejaculating semen. The male urethra is...
Anatomy of the Genitourinary System I: Kidneys and Ureters
Anatomy of the Genitourinary System II: Bladder and Urethra

