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A simple method to obtain a covalent immobilized phospholipase A(2)
1Facultad de Ciencias Agropecuarias, Universidad Nacional de Córdoba, 5000, Córdoba, Argentina. rmadoery@agro.uncor.edu
Bioorganic & Medicinal Chemistry Letters
|June 27, 2001
Abstract:
In the present work, we obtained an immobilized phospholipase A(2) system through covalent coupling by using an acrylic polymer Eupergit C as support. The immobilized enzyme from cobra venom (Naja naja naja) showed good retention activity and excellent stability. Both properties are of great importance for biomedical applications such as hypercholesterolemia treatments.