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Antioxidant activity of water-soluble chitosan derivatives
1Department of Chemistry, Yuquan Campus, Zhejiang University, 310027, Hangzhou, China.
Bioorganic & Medicinal Chemistry Letters
|June 27, 2001
Abstract:
Water-soluble chitosan derivatives were prepared by graft copolymerization of maleic acid sodium onto hydroxypropyl chitosan and carboxymethyl chitosan sodium. Their scavenging activities against hydroxyl radical *OH were investigated by chemiluminescence technique. They exhibit IC(50) values ranging from 246 to 498 microg/mL, which should be attributed to their different contents of hydroxyl and amino groups and different substituting groups.