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Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
Published on: November 23, 2016
A mechanism-based affinity-labeling agent for possible use in isolating N-acetylglucosaminidase
1Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, 21205, Baltimore, MD, USA.
Bioorganic & Medicinal Chemistry Letters
|June 27, 2001
Abstract:
We have prepared several mechanism-based affinity-labeling agents for possible use in isolating N-acetylglucosaminidase, in which an N-acetylglucosamine is linked to an o-monofluoro- or difluoro-methyl phenoxy glycoside with or without a cleavable disulfide group in the tether to biotin.

