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Novel IFN-alpha receptor promoter polymorphisms
1ARC Epidemiology Unit, School of Epidemiology and Health Sciences, University of Manchester, Oxford Road, Manchester, UK.
Genes and Immunity
|June 27, 2001
Abstract:
We have identified two single nucleotide polymorphisms and one dinucleotide microsatellite within the promoter region of the interferon-alpha receptor gene (IFNAR, GenBank accession number X60459). Allele frequencies in a Caucasian population were established using PCR-RFLP for the two SNPs and semi-automated genotyping for the microsatellite.