Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Vasculitis and leukemia.

S Paydaş1, S Zorludemir, B Sahin

  • 1Faculty of Medicine, Department of Oncology, Cukurova University, Balcali, Adana, Turkey. sepay@mail.cu.edu.tr

Leukemia & Lymphoma
|June 28, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Incremental value of binary PSMA PET nodal status when added to Briganti-2019 and MSKCC models for predicting pathologic lymph node metastasis in prostate cancer.

Actas urologicas espanolas·2026
Same author

The effect of acute cold ischemia duration on testicular tissue.

BMC urology·2026
Same author

Comparison of the effectiveness of liposomal doxorubicin and gemcitabine in patients with platinum-sensitive recurrent ovarian cancer receiving third-line chemotherapy.

European review for medical and pharmacological sciences·2023
Same author

Comparison of different cyclin-dependent kinase inhibitors and KI-67 levels on survival and toxicity in breast cancer treatment.

European review for medical and pharmacological sciences·2023
Same author

Awareness and obscurity: demystifying genomic profiling in real-world practice for the members of the Turkish Society of Medical Oncology (TSMO).

European review for medical and pharmacological sciences·2023
Same author

Nasal secretory protein changes following intravenous choline administration in calves with experimentally induced endotoxaemia.

Veterinary immunology and immunopathology·2021

Vasculitis accompanying leukemia can be paraneoplastic or drug-induced. Skin biopsies are crucial for diagnosing vasculitis in patients with hematologic neoplasias, as it can be fatal.

Area of Science:

  • Hematology
  • Dermatology
  • Oncology

Background:

  • Vasculitis can be associated with hematologic neoplasias.
  • It may be paraneoplastic or drug-induced.
  • Cutaneous manifestations require thorough investigation.

Purpose of the Study:

  • To evaluate skin biopsies in patients with leukemia-associated vasculitis.
  • To differentiate between paraneoplastic and drug-induced vasculitis.
  • To assess clinical outcomes and implications for patient management.

Main Methods:

  • Retrospective review of 28 skin biopsies from patients with vasculitis and leukemia.
  • Clinical outcome assessment.
  • Histopathological analysis of skin lesions.

Related Experiment Videos

Main Results:

  • 11 cases of paraneoplastic vasculitis and 17 cases of drug-induced vasculitis were identified.
  • Paraneoplastic vasculitis occurred in chronic myelocytic leukemia (blastic phase), acute myeloblastic leukemia, and myelodysplastic syndromes.
  • Drug-induced vasculitis was linked to chemotherapy, cytokines, and antibiotics.

Conclusions:

  • Paraneoplastic vasculitis is a significant finding in leukemias, particularly in the blastic phase of chronic myeloid leukemia.
  • Drug-induced vasculitis is common and necessitates careful review of patient's medication.
  • Skin biopsy is essential for all cutaneous lesions in patients with hematologic neoplasias to ensure timely diagnosis and management.