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MMR vaccine in HIV-infected children -- potential hazards?
1Imperial College School of Medicine at St. Mary's, Norfolk Place, London W2 1PG, UK. p.goon@ic.ac.uk
Abstract:
Although given routinely as prophylaxis against wild-type measles to HIV-infected children, the live attenuated measles component of the MMR triple vaccine also possesses potential for disease. We document a case of measles proven to be caused by vaccine strain in a HIV-infected child here in the UK and discuss the clinical and immunological aspects. We also consider the new guidelines for MMR vaccination in HIV-infected children adopted last year in the USA.
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