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Sclerosing cholangitis and systemic lymphadenopathy
H Kazumori1, T Hashimoto, S Akagi
1Second Department of Internal Medicine, Shimane Medical University, Izumo, Japan.
Journal of Gastroenterology
|June 29, 2001
Abstract:
A 48-year-old man was admitted to our hospital with jaundice and systemic lymphadenopathy. Cholangiographic findings and liver histology disclosed the presence of sclerosing cholangitis. The patient also had a marked polyclonal increase in IgG levels. The cholangiographic findings, the systemic lymphadenopathy, and the increase in IgG levels resolved completely after treatment with prednisolone. This case suggests that there is an association between sclerosing cholangitis and immunologic abnormalities, and that corticosteroid treatment is useful for this disorder.