Churg-Strauss syndrome
Related Experiment Video
Updated: Sep 29, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
1Division of Pulmonary and Critical Care Medicine and Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA.
Objectives:
This article discusses the clinical manifestations and treatment protocols of Churg-Strauss syndrome (CSS). A review of the definition, pathophysiology, and prognosis of CSS is included, as well as more recent evidence of the presumed association between antileukotriene antagonists and CSS.
Data Sources:
Relevant articles in the medical literature derived from searching the MEDLINE database (1966 to present) with key terms Churg-Strauss syndrome, allergic granulomatosis, and allergic granulomatous angiitis. Sources included review articles, meta-analyses, randomized control trials, case reports, case series, and seminal articles, the majority of which had been published within the past decade.
Study Selection:
Studies that described the clinical manifestations, pathophysiology, etiology, treatment, or prognosis of CSS.
Results:
CSS is a systemic vasculitic disorder with multiorgan involvement and diverse presentations.
Conclusions:
Recognition of the multiorgan manifestations of CSS is crucial to clinical management. Whether a causal relationship exists between antileukotriene antagonists and onset of CSS remains unclear.
More Related Videos
Related Concept Videos
Other Disorders of Digestive System
Esophageal Strictures-I: Introduction
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Endocarditis II: Clinical Features of Infective Endocarditis
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features
Esophageal Achalasia
Cholecystitis

