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Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots
Published on: May 21, 2013
Osteochondral defects of the talus treated with fresh osteochondral allograft transplantation
A E Gross1, Z Agnidis, C R Hutchison
1Mount Sinai Hospital, Toronto, Ontario, Canada. allan.gross@utoronto.ca
Abstract:
Between 1980 and 1996, 9 patients with osteocartilagenous lesions of the talus were treated surgically using fresh osteochondral allograft transplantation. In 8 cases the reason for surgery was osteochondritis dissecans (4 of these cases had a previous traumatic injury). In 1 case a fresh osteochondral allograft of the talus was required following a traumatic open fracture of the talus sustained in a motor vehicle accident. Of these 9 grafts, 6 grafts remain in situ with a mean survival of 11 years (range 4 to 19). In the three cases requiring fusion the reason for surgery was not related to arthritic deterioration but due to resorption and fragmentation of the graft.

