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Updated: Aug 12, 2026
18:48
Murine Renal Transplantation Procedure
Published on: July 10, 2009
Infective endocarditis in renal transplant recipients
J Bishara1, E Robenshtok, M Weinberger
1Department of Internal Medicine C, Rabin Medical Center, Beilinson Campus, Sackler School of Medicine, Tel Aviv University, Petach Tikvah, Israel.
Summary
Infective endocarditis is rare in renal transplant recipients, often caused by unusual microbes. These infections present atypically and have a high mortality rate, necessitating further research.
Area of Science:
- Nephrology
- Infectious Diseases
- Cardiology
Background:
- Renal transplantation rates are rising globally.
- Infective endocarditis (IE) is a rare complication in transplant recipients.
- Understanding IE in this population is crucial for improved patient outcomes.
Observation:
- This study reviewed 14 cases of IE in renal transplant recipients, including 2 new cases.
- The average time from transplant to IE diagnosis was 3.5 years.
- Common causative agents included fungi, Staphylococcus aureus, and Corynebacterium species, alongside rarer pathogens.
Findings:
- IE in renal transplant recipients presents with atypical clinical features, lacking typical skin manifestations and splenomegaly.
- Septic emboli and mycotic aneurysms were frequently observed.
- The overall mortality rate for IE in this cohort was 50%.
Implications:
- IE in renal transplant recipients is characterized by unusual pathogens and atypical presentations.
- The high mortality rate underscores the severity of this condition.
- Further research is required to fully understand the scope and management of IE in renal transplant recipients.
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