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Updated: Aug 1, 2026

The Three-Dimensional Human Skin Reconstruct Model: a Tool to Study Normal Skin and Melanoma Progression
Published on: August 3, 2011
Reconstruction of superficial skin cancer defects of the nose
1Oral and Maxillofacial Surgery, University of Texas, Southwestern Medical Center, Dallas, TX, USA.
Purpose:
This article reviewed the results of reconstruction of surface nasal defects after removal of skin cancer.
Patients And Methods:
One hundred patients with 103 surface defects involving various locations on the nose were treated. Management included direct closure, secondary epithelization, full-thickness skin grafts, and local flaps using 1 or 2 stages.
Results:
Ten nasal defects were treated by direct closure, 8 defects healed by secondary epithelization, and 30 patients were treated with a full-thickness skin graft. Fifty-five defects were reconstructed with local flaps including 30 one-stage and 25 two-stage flaps.
Conclusion:
Many options are available for reconstructing nasal defects that can lead to acceptable aesthetic results. Among the factors that need to be addressed before choosing a procedure for reconstruction of surface nasal defects resulting from skin cancer are size and location of the defect, aesthetic concerns, and the medical status of the patient.
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