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Vertilecanins: new phenopicolinic acid analogues from Verticillium lecanii
A G Soman1, J B Gloer, R F Angawi
1Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, USA.
Journal of Natural Products
|June 30, 2001
Abstract:
Five new phenopicolinic acid analogues (1-5) have been isolated from solid-substrate fermentation cultures of Verticillium lecanii. The most abundant component (vertilecanin A; 1) displays antiinsectan activity against Helicoverpa zea. These compounds were obtained by chromatographic fractionation of the EtOAc culture extract and identified by analysis of NMR and MS data. The known fungal metabolites 2-decenedioic acid and 10-hydroxy-8-decenoic acid were also isolated from these cultures.