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Depression and anxiety disorders.

C S Brown1

  • 1Departments of Pharmacy Practice and Pharmacoeconomics, Obstetrics and Gynecology, and Psychiatry, University of Tennessee Health Science Center, Memphis, Tennessee, USA.

Obstetrics and Gynecology Clinics of North America
|June 30, 2001
PubMed
Summary
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Women are more prone to depressive and anxiety disorders, requiring careful management during pregnancy and postpartum. Selective serotonin reuptake inhibitors (SSRIs) are often the first-line treatment for these common conditions.

Area of Science:

  • Obstetrics and Gynecology
  • Psychiatry
  • Women's Health

Background:

  • Depressive and anxiety disorders are prevalent in women, affecting them at twice the rate of men.
  • These conditions encompass major depression, dysthymia, seasonal affective disorder, premenstrual dysphoric disorder, panic disorder, generalized anxiety disorder, social phobia, obsessive compulsive disorder, and PTSD.
  • Management is crucial during pregnancy, postpartum, and breastfeeding.

Purpose of the Study:

  • To outline diagnostic and management principles for depressive and anxiety disorders in women.
  • To review first-line and alternative pharmacologic treatments.
  • To emphasize the importance of suicide risk assessment and psychotherapy.

Main Methods:

  • Review of current treatment guidelines and clinical experience.

Related Experiment Videos

  • Discussion of selective serotonin reuptake inhibitors (SSRIs) as first-line therapy.
  • Exploration of alternative antidepressants like venlafaxine, bupropion, nefazodone, and mirtazapine.

    • Main Results:

    • SSRIs demonstrate efficacy, require minimal titration, have a favorable side-effect profile, and extensive clinical data.
    • Alternative antidepressants are available for non-responsive or intolerant patients.
    • Comprehensive management includes psychotherapy, pharmacotherapy, and medical work-up.

    Conclusions:

    • Effective diagnosis and management of depressive and anxiety disorders are essential for obstetrician-gynecologists.
    • SSRIs are recommended as the initial pharmacologic treatment.
    • Referral to mental health specialists is guided by specific protocols.