Related Experiment Video
Updated: Oct 5, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
A program for treating olanzapine-related weight gain
M P Ball1, V B Coons, R W Buchanan
1Maryland Psychiatric Research Center at the University of Maryland School of Medicine, Baltimore 21228, USA. pball@mprc.umaryland.edu
Abstract:
This study evaluated the effectiveness of a Weight Watchers program for patients with schizophrenia who had olanzapine-related weight gain and ascertained whether the severity of patients' psychiatric symptoms was correlated with the patients' success in losing weight. Seven men and four women who had been treated with olanzapine and who had gained at least 7 percent of their pretreatment body weight attended Weight Watchers meetings and were offered supervised exercise sessions. The patients' weight, body mass index, and psychiatric symptoms were assessed and were compared with those of a matched comparison group who did not attend the Weight Watchers program. Only the men experienced significant weight loss. No correlation was found between weight loss and exercise or change in psychiatric symptoms.
Related Concept Videos
Psychosis: Goals of Pharmacotherapy
Antidepressant Drugs: MAOIs and Other Agents
Antipsychotic Drugs: Therapeutic Uses and Side Effects
Despite these side effects, antipsychotics are used therapeutically for various purposes, including managing schizophrenia, preventing nausea and vomiting, curbing...
Antipsychotic Drugs: Typical and Atypical Agents
Drug Dosing: Obese Patients
Antiepileptic Drugs: Potassium Channel Activators
Ezogabine has gained approval as an adjunctive treatment...
