Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Insecticidal proteins from Bacillus thuringiensis protect corn from corn rootworms.

D J Moellenbeck1, M L Peters, J W Bing

  • 1Pioneer Hi-Bred International, Inc., 7250 NW 62nd Avenue, P.O. Box 552, Johnston, IA 50131-0552, USA. DAN.MOELLENBECK@pioneer.com

Nature Biotechnology
|July 4, 2001
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

6,10,14-Trimethylpentadecan-2-one: A Bermuda grass phagostimulant to fall armyworm (lepidoptera: Noctuidae).

Journal of chemical ecology·2013
Same author

Coculturing embryonic stem cells with damaged hepatocytes leads to restoration of damage and high frequency of fusion.

Cellular and molecular biology (Noisy-le-Grand, France)·2009
Same author

Role of interleukin 33 in human immunopathology.

Annals of the rheumatic diseases·2009
Same author

Dual roles of Drosophila p53 in cell death and cell differentiation.

Cell death and differentiation·2009
Same author

Diffusion-weighted imaging in fetuses with unilateral cortical malformations and callosal agenesis.

AJNR. American journal of neuroradiology·2009
Same author

Sjogren's syndrome-onset lupus patients have distinctive clinical manifestations and benign prognosis: a case-control study.

Lupus·2009
Same journal

Unlocking the chemical potential of filamentous fungi using prime editing.

Nature biotechnology·2026
Same journal

A genome-scale CRISPRi perturbation atlas of human induced pluripotent stem cells.

Nature biotechnology·2026
Same journal

Prime editing for precise genome engineering and modulation of fungal metabolism.

Nature biotechnology·2026
Same journal

Retargeted serine integrases for one-step, precise integration of large DNA sequences in human cells.

Nature biotechnology·2026
Same journal

A retargeted recombinase for precise insertion of large DNA.

Nature biotechnology·2026
Same journal

Experiment-guided AlphaFold3 resolves measurement-consistent protein ensembles.

Nature biotechnology·2026
See all related articles
This summary is machine-generated.

New Bacillus thuringiensis (Bt) corn varieties offer superior protection against western corn rootworm damage compared to chemical insecticides. Field tests show these genetically modified crops effectively control rootworm pests.

Area of Science:

  • Agricultural Science
  • Entomology
  • Molecular Biology

Background:

  • Western corn rootworm (Diabrotica virgifera virgifera LeConte) poses a significant threat to corn crops.
  • Chemical insecticides are commonly used but face challenges with efficacy and environmental impact.

Purpose of the Study:

  • To evaluate the efficacy of corn engineered to express two novel Bacillus thuringiensis (Bt) delta-endotoxins against western corn rootworm.
  • To compare the protective effects of Bt-expressing corn with conventional chemical insecticides.

Main Methods:

  • Field trials were conducted using corn varieties co-expressing 14 kDa and 44 kDa Bt delta-endotoxins.
  • Corn rootworm larvae were exposed to engineered corn roots in controlled and field conditions.
  • Histopathological analysis of larval midguts was performed.

Related Experiment Videos

Main Results:

  • Corn expressing the two Bt delta-endotoxins provided significant protection against western corn rootworm root damage.
  • The level of protection achieved surpassed that of standard chemical insecticides.
  • Larvae feeding on engineered corn exhibited histopathological damage in their midgut epithelium.

Conclusions:

  • Co-expression of novel Bt delta-endotoxins in corn offers a highly effective strategy for managing western corn rootworm.
  • This approach presents a promising alternative to chemical insecticides for sustainable agriculture.