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Leptin and HDL-cholesterol in non-diabetic normotensive subjects
G M Marinari1, N Scopinaro, G F Adami
1Dipartimento di Discipline Chirurgiche e Metodologie Integrate, Università di Genova, Italy.
Background:
We investigated the relationships between body mass index (BMI), serum leptin and serum HDL-cholesterol.
Material And Methods:
A retrospective study was carried out in 80 patients who did not have type 2 diabetes mellitus and/or high blood pressure.
Results:
Both serum leptin and HDL-cholesterol serum levels correlated with BMI (r = 0.616 and r = -0.269, respectively), but when the BMI values were kept constant no correlation was found between serum leptin and HDL-cholesterol both in simple and in multiple regression.
Conclusion:
The findings suggest that serum leptin concentration is completely independent of lipid metabolism.
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