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[Peritonitis in children treated with automated peritoneal dialysis]
A Zurowska1, I Bałasz, I Zagozdzon
1Klinika Nefrologii Dzieciecej, Akademii Medycznej w Gdańsku.
Summary
Children on automated peritoneal dialysis (APD) experienced significantly lower peritonitis rates compared to continuous ambulatory peritoneal dialysis (CAPD). Treatment efficacy and relapse rates were similar between APD and CAPD methods.
Area of Science:
- Pediatric Nephrology
- Renal Replacement Therapy
Background:
- Peritonitis is a significant complication in children undergoing peritoneal dialysis.
- Understanding the comparative risks and benefits of different peritoneal dialysis modalities is crucial for patient management.
Purpose of the Study:
- To compare the incidence of peritonitis between automated peritoneal dialysis (APD) and continuous ambulatory peritoneal dialysis (CAPD) in pediatric patients.
- To evaluate the etiology of peritonitis and the efficacy of treatment across both APD and CAPD modalities.
Main Methods:
- A comparative study involving 28 children on APD (439 dialysis months) and 24 children on CAPD (328 dialysis months).
- Analysis of peritonitis rates, causative organisms, treatment success, and relapse rates for both dialysis methods.
Main Results:
- The peritonitis rate was significantly lower in children on APD (1 episode per 27 months) compared to CAPD (1 episode per 17 months) (p = 0.005).
- No significant differences were observed in the etiology of peritonitis (predominantly Gram-positive organisms), treatment efficacy (100% in both groups), or relapse rates between APD and CAPD.
Conclusions:
- Automated peritoneal dialysis is associated with a reduced risk of peritonitis in pediatric patients compared to CAPD.
- Both APD and CAPD demonstrate comparable efficacy in treating peritonitis and similar relapse rates, with similar etiological profiles.