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Published on: October 12, 2017
[Vesicoureteral refluxes in children during the first two years of life]
G Krzemień1, M Roszkowska-Blaim, I Kostro
1Katedra i Klinika Pediatrii i Nefrologii Akademii Medycznej w Warszawie.
Insights
Vesicoureteral reflux (VUR) in young children often resolves with conservative management, with most cases disappearing within 13.7 months. Recurrent urinary tract infections (UTIs) occurred in 15.6% of children.
Area of Science:
- Pediatric Nephrology
- Urology
- Diagnostic Imaging
Background:
- Vesicoureteral reflux (VUR) is a common condition in children, often diagnosed following urinary tract infections (UTIs).
- Understanding the natural history and treatment outcomes of VUR is crucial for pediatric patient management.
Purpose of the Study:
- To analyze the incidence, characteristics, and treatment outcomes of VUR in children diagnosed by age two.
- To evaluate the effectiveness of conservative management and identify factors influencing VUR resolution.
Main Methods:
- Retrospective study of 96 children diagnosed with VUR by age two.
- Analysis of VUR laterality, coexisting abnormalities, diagnostic imaging findings (USG), and treatment approaches (conservative vs. surgical).
- Follow-up using voiding cystourethrography to assess VUR resolution rates and recurrent UTIs.
Main Results:
- VUR was diagnosed in 143 cases, with 51% unilateral and 49% bilateral; 14.6% had coexisting urinary tract abnormalities.
- Conservative treatment was initiated in 88% of VUR cases and proved successful in 68.6%.
- VUR resolved in 70.9% of cases after a mean follow-up of 13.7 months, with higher resolution rates in higher grades of VUR.
Conclusions:
- Conservative management is highly effective for pediatric VUR, leading to spontaneous resolution in a majority of cases.
- Recurrent UTIs were observed in 15.6% of children, necessitating surgical intervention in a small percentage.
- Early diagnosis and appropriate management, primarily conservative, are key to favorable outcomes in pediatric VUR.
Abstract:
Ninety-six children with vesicoureteral reflux (VUR) diagnosed by age 2 were studied. The most common indication for radiological visualization of the urinary tract was a urinary tract infection (UTI). Among 143 cases of VUR, 51% were unilateral and 49% were bilateral. Other urinary tract abnormalities coexisted with VUR in 14.6% of children. Abnormal USG result was found in 24% of children, including only 13.4% with VUR and other urinary tract abnormalities. Conservative treatment was chosen in 126 (88%) cases of VUR in 87.5% of children. Follow-up voiding cystourethrography was performed in 60.7% of children. Conservative treatment was successful in 68.6% of children. VUR disappeared in 70.9% of cases after mean follow-up of 13.7 months (including 76.2% cases of VUR grade II, 54.5% cases of VUR grade III and 50% cases of VUR grade I). Recurrent UTI and lack of improvement after conservative treatment were indications for surgical treatment in 9.8% of children. Recurrent UTI were observed in 15.6% of children (including 16.7% among those treated conservatively and 8.3% among those treated surgically) and their course was febrile in most cases.
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