Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Computer simulation of particle overlap in fiber count samples.

C C Chen1, T S Yu, T S Shih

  • 1Institute of Occupational Medicine and Industrial Hygiene, College of Public Health, National Taiwan University, Taipei.

AIHAJ : a Journal for the Science of Occupational and Environmental Health and Safety
|July 4, 2001
PubMed
Summary

Accurate fibrous aerosol measurement requires understanding filter loading limits. This study identifies upper concentration limits for reliable fiber counting, crucial for industrial hygienists assessing health risks.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Morphine augmentation increases gallbladder visualization in patients pretreated with cholecystokinin.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·1997
Same author

Right-sided cardiac tumors detected by transesophageal echocardiography and its usefulness in differentiating the benign from the malignant ones.

The American journal of cardiology·1997
Same author

Postoperative MRI of anorectal malformation.

Journal of the Formosan Medical Association = Taiwan yi zhi·1997
Same author

Value of somatostatin receptor scintigraphy: a prospective study in gastrinoma of its effect on clinical management.

Gastroenterology·1997
Same author

Blood levels of reduced haloperidol versus clinical efficacy and extrapyramidal side effects of haloperidol.

Progress in neuro-psychopharmacology & biological psychiatry·1997
Same author

The binge eating and emotional change in a patient with postinfectious encephalomyelitis.

The Kaohsiung journal of medical sciences·1997

Area of Science:

  • Occupational health and safety
  • Industrial hygiene
  • Aerosol science

Background:

  • Inhaling fibrous aerosols poses significant health risks.
  • Previous research suggests optimal filter loading densities (100-1300 fibers/mm²) to minimize bias in fiber counts.
  • Overlapping fibers and particles on filters can lead to measurement errors.

Purpose of the Study:

  • To determine the upper limits for fiber and particle concentrations for reliable counting and identification.
  • To explore methods for correcting fiber counts affected by particle or fiber overlap.
  • To assess the impact of filter loading density and particle characteristics on counting accuracy.

Main Methods:

  • Simulated a light microscope graticule field using a computer-generated grid with 2000x2000 resolution.

Related Experiment Videos

  • Utilized bivariate lognormal distributions to model fiber length and width.
  • Investigated parameters including resolution index, graticule coverage, filter loading density, size distributions, and fiber-to-particle concentration ratio.

    • Main Results:

    • Counting efficiency decreased with increased filter surface loading density and decreased resolution index.
    • The optimal upper limit for filter surface fiber density is dependent on concentration ratios, loading densities, and size distributions.
    • Using a thoracic preseparator significantly improved counting efficiency for nonfibrous particles near or exceeding the 10-micrometer cutoff.

    Conclusions:

    • Establishing appropriate filter loading densities is critical for accurate fibrous aerosol assessment.
    • A procedure for correcting fiber counts due to overlap can improve reliability.
    • Thoracic preseparators enhance counting efficiency, particularly with larger nonfibrous particles.